Time is ticking

They have changed into a spellbound person and won’t listen to anyone. When your spouse tells you the drugs HELP them and they tell you they want to trust the doctors and not you and will not taper off, then they very likely won’t ever change. They will go through life as a completely different person and one that more than likely rewrites your past history, has no empathy, is apathetic, loses their moral compass, and on and on. Not someone you will be able to live with for a long time.