Wife wants divorce on 150 mg of sertaline

“My wife has been on 150mg of sertraline for two and a half years now. She’s changed drastically, and now wants a divorce. I hate what this medication has done to her. She shows zero emotion or affection to our kids ( a 4 & 5 year old) or me. She’s always on edge and full of anger. I’ve tried to show her this group and she will not accept it, any ideas how to get her to want to taper.”