Serotonin targeting drugs worksheet

Serotonin Changes Under Psychotropic Drugs — Tracking Worksheet
HARMED Hearts • Harmed.LifeSerotonin drugs can affect more than mood.

Serotonin Changes Under Psychotropic Drugs — Tracking Worksheet

For patients and loved ones to track observable changes and discuss with clinicians.

Serotonin influences mood, sleep, appetite, thinking, movement, and more. When SSRIs, SNRIs, or other psychotropics alter serotonin signaling, changes may appear in the areas below. This worksheet is for tracking and discussion; it is not medical advice.
Name:
Date:
Medication & dose:
Clinician:

How to Rate

Rate each item today: 1 = Not at all2 = Mild3 = Moderate4 = Marked5 = Severe

Part 1 — Emotional & Personality Changes

Item (observed)12345
Emotional blunting / numbness
Decreased empathy
Irritability / agitation
Sudden anger / hostility
Loss of personality “spark”

Part 2 — Cognitive & Behavioral Changes

Item (observed)12345
Impulsivity / risky behavior
Poor judgment
Difficult decisions / indecisiveness
Obsessive or racing thoughts
Confusion / slowed thinking
Memory lapses

Part 3 — Physical & Nervous System Changes

Item (observed)12345
Sleep changes (insomnia / vivid dreams)
Appetite changes / weight shifts
Sexual function changes (desire, arousal, orgasm)
Sweating / temperature swings
Movement problems (tremor, akathisia, restlessness)
Headache / dizziness

Part 4 — Mood & Safety Concerns

Item (observed)12345
Anxiety spikes / panic
Depression increases
Sudden suicidal thoughts
Loss of motivation / apathy
Rapid mood swings (up/down)
Paranoia / suspiciousness

Examples / Notes

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