leydig-cell evidence

Serotonin and Testosterone reduction Serotonin, SSRIs, and Testosterone: Brief Citation Sheet for Clinical ReviewClinical bottom line:Current evidence supports a biologically plausible link between serotonergic signaling and reduced testosterone production, with the strongest direct evidence coming from Leydig-cell and animal studies. In humans, there is evidence that SSRIs can disrupt the hypothalamic-pituitary-testicular axis and are associated…